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University College of Engineering
Bharathidasan Institute of Technology Campus
Anna University, Tiruchirappalli - 620 024.

University College of Engineering
Bharathidasan Institute of Technology Campus
Anna University, Tiruchirappalli - 620 024.

NFDD Facilities

Facilities

The Make & Model of the sophisticated equipments available are

LC-MS/ MS

01

Equipment

LC-MS/ MS

Make

Bruker Daltonics

Model

MicrOTOF-Q III with APCI Source & Dionex Ultimate 3000 RSLC LCMS/MS has a mass Range (extended) 20-3000 m/z (20-20000 m/z), Mass accuracy better than 3 ppm RMS Error (internal) and 5 ppm RMS Error (external) for both MS and MS/MS spectra, Mass resolution of 20,000 (FWHM) and a True Isotopic Pattern (TIP) for both MS and MS/MS spectra. All parameters are delivered simultaneously to provide the most complete insight into the sample.

Application

Small Molecule Identification of the unknown analyte, Target Screening Multiple target screening, Metabolomics study LC-MS based Screening (biological and plant metabolomics), Proteomics Analysis of Intact Protein Identification, Bioavailability studies, Drug metabolism studies, pharmacokinetics, Characterization of potential drugs, Drug degradation product analysis, Screening of drug candidates, Identifying drug targets, Biomolecule characterization-Proteins and peptides, Oligonucleotides, Environmental analysis-Pesticides on foods Soil and groundwater contamination, Forensic analysis/clinical

U(H)PLC

01

Equipment

U(H)PLC

Make

Shimadzu

Model

Nexera UPLC Ultra high performance liquid chromatography means the highest resolution, highest sensitivity and fastest analysis-in other words, a superlative LC system.

Application

Analysis of Biogenic substances-Sugar, lipid, nucleic acids, amino acids, proteins, peptides, steroids, amides; Medical products-Drugs, antibiotics; Food products-Vitamins, food additives, sugars, organic acids, amino acids; Organic industrial products-Synthetic polymers, additives, surfactants.

UV-Visible Spectrophotometer

01

Equipment

UV-Visible Spectrophotometer

Make

Shimadzu

Model

UV-2600 Spectrophotometer with Integrating sphere ISR-2600plus UV/Vis spectroscopy is routinely used in the quantitative determination of solutions of transition metal ions, highly conjugated organic compounds, and biological macromolecules.

Application

Detection of impurities, structure elucidation of organic compounds, quantitative analysis, qualitative analysis, chemical kinetics, detection of functional group, quantitative analysis of pharmaceutical substances, examination of polynuclear hydrocarbons, molecular weight determination.

Nano Particle and Zeta Potential Analyzer

01

Equipment

Nano Particle and Zeta Potential Analyzer

Make

Malvern

Model

NANO ZS Series Nano Particle Size and Zeta Potential Analyser permits accurate zeta potential measurement in a wide concentration range of 0.00001 to 40% (w/v), eliminating the need to dilute samples.

Application

Measurement of the size, electrophoretic mobility of proteins, zeta potential of colloids and nanoparticles, colloid and emulsion characterization, high sensitivity of nanoparticles, proteins and macromolecules, optimize the formulations of suspensions and emulsions.

HPTLC

01

Equipment

HPTLC

Make

CAMAG

Model

HPTLC System, HPTLC helps to identify and quantify the active constituents present in the herbal extracts.

Application

Biochemical Research, Clinical, Cosmetics, Environmental Analysis, Food Analysis, Pharmaceuticals, Natural Products, Plant Ingredients, Toxicology, Forensic Analysis, Doping Analysis

Multimode Micro Plate Reader

01

Equipment

Multimode Micro Plate Reader

Make

Perkin Elmer

Model

Enspire Multi Label Plate Reader, Multimode Microplate Readers are used for analyzing samples in micro-titre volumes with the detection modes of spectral absorbance, fluorescence and luminescence, in the field of drug discovery research and bioassay validation.

Application

Enzyme kinetics and end-point assays , Cell signalling & imaging assays, Cell proliferation, viability & toxicity studies, Fluorescent protein expression, Bio & Chemiluminescence, Ion Channels flux assays & Imaging, Immunoassays, Molecular interactions, Nucleic acid and Protein Quantitation.

Inverted Fluorescence Microscope

01

Equipment

Inverted Fluorescence Microscope

Make

Nikon

Model

TiE Inverted Microscopes are ubiquities analytical instruments in which the body, ocular and objective are located underneath the stage, while the specimen is illuminated from above.

Application

To study the living cells and tissue cultures with Phase contrast, Fluorescent, Multi-dimensional Imaging, Nomarski DIC, Time-lapse and Live Cell Imaging techniques. Visualization, Measurement and analysis of microstructures.

Gel Documentation System

01

Equipment

Gel Documentation System

Make

BIORAD

Model

Gel Doc EZ Imager, Gel documentation or gel imaging systems are used to record and measure labelled nucleic acid and protein in various types of media such as agarose, acrylamide or cellulose.

Application

Detection and Quantification of Genes & Proteins based on their sizes by Gel & Western Blot imaging, Monoclonal & Polyclonal Binding Affinities, Post-Translational Modification Characterization, 2D Electrophoresis, UV & Fluorescence imaging, Colony counting and Immunoassays.

Airway Mechanical Analyzer

01

Equipment

Airway Mechanical Analyzer

Make

Emka Technologies,France

Model

Whole Body Plethysmograph & Double chamber Plethysmograph with IOX-FULL PULMO software The non invasive whole body plethysmography, is proven way to study pulmonary function and evaluate bronchoconstriction on unrestrained conscious animals. The non invasive measurements results in less strain placed on the animals and allows repeated testing of the same animal at multiple time points. Double chamber Plethysmograph is used to study the specific airway measurements on restrained conscious animals.

Application

Experimental asthma studies in rodents, Experimental cough studies in guinea pigs, Allergen induced airway measurements, pulmonary function testing in rodents.

Airway Mechanical Analyzer

01

Equipment

Nano Particle and Zeta Potential Analyzer

Make

SCIREQ, Canada

Model

Inhalation Exposure Inexpose base unit with accessories & Inexpose-Flexi ware software inExpose (Scireq Inc) is an integrated and compact tool for exposing subjects to profiles of pharmacological compounds, cigarette smoke and other toxins.

Application

The inExpose permits a wide range of gases, airborne substances and pollutants to be delivered to the subjects via the exposure systems. Inhalation exposure studies using a wide range of aerosolized drugs and compounds, cigarette smoke and a variety of other toxins.

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