NFDD Facilities
Facilities
The Make & Model of the sophisticated equipments available are
LC-MS/ MS
01
Equipment
LC-MS/ MS
Make
Bruker Daltonics
Model
MicrOTOF-Q III with APCI Source & Dionex Ultimate 3000 RSLC LCMS/MS has a mass Range (extended) 20-3000 m/z (20-20000 m/z), Mass accuracy better than 3 ppm RMS Error (internal) and 5 ppm RMS Error (external) for both MS and MS/MS spectra, Mass resolution of 20,000 (FWHM) and a True Isotopic Pattern (TIP) for both MS and MS/MS spectra. All parameters are delivered simultaneously to provide the most complete insight into the sample.
Application
Small Molecule Identification of the unknown analyte, Target Screening Multiple target screening, Metabolomics study LC-MS based Screening (biological and plant metabolomics), Proteomics Analysis of Intact Protein Identification, Bioavailability studies, Drug metabolism studies, pharmacokinetics, Characterization of potential drugs, Drug degradation product analysis, Screening of drug candidates, Identifying drug targets, Biomolecule characterization-Proteins and peptides, Oligonucleotides, Environmental analysis-Pesticides on foods Soil and groundwater contamination, Forensic analysis/clinical
U(H)PLC
01
Equipment
U(H)PLC
Make
Shimadzu
Model
Nexera UPLC Ultra high performance liquid chromatography means the highest resolution, highest sensitivity and fastest analysis-in other words, a superlative LC system.
Application
Analysis of Biogenic substances-Sugar, lipid, nucleic acids, amino acids, proteins, peptides, steroids, amides; Medical products-Drugs, antibiotics; Food products-Vitamins, food additives, sugars, organic acids, amino acids; Organic industrial products-Synthetic polymers, additives, surfactants.
UV-Visible Spectrophotometer
01
Equipment
UV-Visible Spectrophotometer
Make
Shimadzu
Model
UV-2600 Spectrophotometer with Integrating sphere ISR-2600plus UV/Vis spectroscopy is routinely used in the quantitative determination of solutions of transition metal ions, highly conjugated organic compounds, and biological macromolecules.
Application
Detection of impurities, structure elucidation of organic compounds, quantitative analysis, qualitative analysis, chemical kinetics, detection of functional group, quantitative analysis of pharmaceutical substances, examination of polynuclear hydrocarbons, molecular weight determination.
Nano Particle and Zeta Potential Analyzer
01
Equipment
Nano Particle and Zeta Potential Analyzer
Make
Malvern
Model
NANO ZS Series Nano Particle Size and Zeta Potential Analyser permits accurate zeta potential measurement in a wide concentration range of 0.00001 to 40% (w/v), eliminating the need to dilute samples.
Application
Measurement of the size, electrophoretic mobility of proteins, zeta potential of colloids and nanoparticles, colloid and emulsion characterization, high sensitivity of nanoparticles, proteins and macromolecules, optimize the formulations of suspensions and emulsions.
HPTLC
01
Equipment
HPTLC
Make
CAMAG
Model
HPTLC System, HPTLC helps to identify and quantify the active constituents present in the herbal extracts.
Application
Biochemical Research, Clinical, Cosmetics, Environmental Analysis, Food Analysis, Pharmaceuticals, Natural Products, Plant Ingredients, Toxicology, Forensic Analysis, Doping Analysis
Multimode Micro Plate Reader
01
Equipment
Multimode Micro Plate Reader
Make
Perkin Elmer
Model
Enspire Multi Label Plate Reader, Multimode Microplate Readers are used for analyzing samples in micro-titre volumes with the detection modes of spectral absorbance, fluorescence and luminescence, in the field of drug discovery research and bioassay validation.
Application
Enzyme kinetics and end-point assays , Cell signalling & imaging assays, Cell proliferation, viability & toxicity studies, Fluorescent protein expression, Bio & Chemiluminescence, Ion Channels flux assays & Imaging, Immunoassays, Molecular interactions, Nucleic acid and Protein Quantitation.
Inverted Fluorescence Microscope
01
Equipment
Inverted Fluorescence Microscope
Make
Nikon
Model
TiE Inverted Microscopes are ubiquities analytical instruments in which the body, ocular and objective are located underneath the stage, while the specimen is illuminated from above.
Application
To study the living cells and tissue cultures with Phase contrast, Fluorescent, Multi-dimensional Imaging, Nomarski DIC, Time-lapse and Live Cell Imaging techniques. Visualization, Measurement and analysis of microstructures.
Gel Documentation System
01
Equipment
Gel Documentation System
Make
BIORAD
Model
Gel Doc EZ Imager, Gel documentation or gel imaging systems are used to record and measure labelled nucleic acid and protein in various types of media such as agarose, acrylamide or cellulose.
Application
Detection and Quantification of Genes & Proteins based on their sizes by Gel & Western Blot imaging, Monoclonal & Polyclonal Binding Affinities, Post-Translational Modification Characterization, 2D Electrophoresis, UV & Fluorescence imaging, Colony counting and Immunoassays.
Airway Mechanical Analyzer
01
Equipment
Airway Mechanical Analyzer
Make
Emka Technologies,France
Model
Whole Body Plethysmograph & Double chamber Plethysmograph with IOX-FULL PULMO software The non invasive whole body plethysmography, is proven way to study pulmonary function and evaluate bronchoconstriction on unrestrained conscious animals. The non invasive measurements results in less strain placed on the animals and allows repeated testing of the same animal at multiple time points. Double chamber Plethysmograph is used to study the specific airway measurements on restrained conscious animals.
Application
Experimental asthma studies in rodents, Experimental cough studies in guinea pigs, Allergen induced airway measurements, pulmonary function testing in rodents.
Airway Mechanical Analyzer